Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of neurodevelopmental outcomes of extremely preterm infants undergoing trans-catheter closure of the patent ductus arteriosus compared to surgical ligation.

Journal of perinatology : official journal of the California Perinatal Association·2025
Same author

Neurodevelopmental outcomes among extremely premature infants with linear growth restriction.

Journal of perinatology : official journal of the California Perinatal Association·2018
Same author

Barriers to enrollment in a randomized controlled trial of hydrocortisone for cardiovascular insufficiency in term and late preterm newborn infants.

Journal of perinatology : official journal of the California Perinatal Association·2017
Same author

Neurodevelopmental outcomes in postnatal growth-restricted preterm infants with postnatal head-sparing.

Journal of perinatology : official journal of the California Perinatal Association·2016
Same author

Inhaled nitric oxide usage in preterm infants in the NICHD Neonatal Research Network: inter-site variation and propensity evaluation.

Journal of perinatology : official journal of the California Perinatal Association·2014
Same author

Outcomes of extremely preterm infants following severe intracranial hemorrhage.

Journal of perinatology : official journal of the California Perinatal Association·2013
Same journal

Impact of Kaiser permanente early-onset sepsis risk calculator implementation in hospitals, England: pre-post intervention cohort analysis.

Archives of disease in childhood. Fetal and neonatal edition·2026
Same journal

Postnatally acquired cytomegalovirus infection in preterm infants: an update on diagnosis, management and outcomes.

Archives of disease in childhood. Fetal and neonatal edition·2026
Same journal

High versus low PEEP in the delivery room: a preimplementation and postimplementation cohort study.

Archives of disease in childhood. Fetal and neonatal edition·2026
Same journal

Trends in the incidence of low-grade intraventricular haemorrhage among preterm babies: a national cohort study.

Archives of disease in childhood. Fetal and neonatal edition·2026
Same journal

Apnoeic oxygenation with nasal high flow during neonatal intubation: a prospective audit.

Archives of disease in childhood. Fetal and neonatal edition·2026
Same journal

Visual acuity assessments at 5 years in a national cohort (EPIPAGE-2).

Archives of disease in childhood. Fetal and neonatal edition·2026
See all related articles

Related Experiment Video

Updated: Jul 3, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
06:27

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Published on: December 31, 2015

When to transfuse preterm babies.

E F Bell1

  • 1Department of Pediatrics, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA. edward-bell@uiowa.edu

Archives of Disease in Childhood. Fetal and Neonatal Edition
|July 26, 2008
PubMed
Summary
This summary is machine-generated.

Delaying umbilical cord clamping and limiting blood draws can reduce red blood cell transfusions in preterm infants. Current transfusion guidelines need further research for optimal safety and long-term outcomes.

More Related Videos

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
08:58

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

Related Experiment Videos

Last Updated: Jul 3, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
06:27

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Published on: December 31, 2015

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
08:58

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

Area of Science:

  • Neonatal Medicine
  • Pediatric Hematology
  • Clinical Transfusion Practices

Background:

  • Preterm infants experience physiological anemia, worsened by routine care like early cord clamping and frequent phlebotomy.
  • Red blood cell transfusions are common but carry risks and resource implications.

Purpose of the Study:

  • To evaluate the impact of transfusion guidelines on red blood cell transfusion needs in preterm infants.
  • To analyze evidence regarding restrictive versus liberal transfusion strategies.

Main Methods:

  • Analysis of two large clinical trials comparing restrictive and liberal transfusion guidelines.
  • Review of factors influencing transfusion requirements, including cord clamping and phlebotomy.

Main Results:

  • Restrictive transfusion guidelines may decrease transfusion frequency but not necessarily donor exposures with single-donor programs.
  • Some evidence suggests liberal guidelines might aid in preventing brain injury.
  • Long-term outcome data related to transfusion practices is currently lacking.

Conclusions:

  • Current evidence does not support using transfusion thresholds lower than those in recent trials due to safety concerns.
  • Optimizing transfusion guidelines requires further research to balance benefits and risks, especially concerning long-term outcomes.