Related Experiment Video
Updated: Jul 3, 2026

07:34
Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits
Published on: June 2, 2019
Angiogenesis achieved by granulocyte colony-stimulating factor in combination with bypass surgery in 2 cases of
Mitsuyuki Nakayama1, Yasuhiro Asari
1Department of Vascular Surgery, Kanoiwa Hospital, Yamanashi, Japan. mitsu88@mx5.nns.ne.jp
Abstract:
Patients demonstrating critical limb ischemia with a long-distance occlusion of the major arteries are sometimes poor candidates for bypass surgery, because tandem occlusion complicates distal anastomoses and poor run-off causes early occlusion of bypass grafts. In order to resolve these problems, angiogenesis therapy was attempted by subcutaneous injection of granulocyte colony-stimulating factor either before or after peripheral bypass surgery in 2 cases.

