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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

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Updated: Jul 3, 2026

Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography-Computed Tomography Scanner
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Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography-Computed Tomography Scanner

Published on: June 7, 2024

Perfusion imaging with computed tomography: brain and beyond.

Kenneth A Miles1

  • 1Division of Clinical and Laboratory Investigation, Brighton and Sussex Medical School, University of Sussex, Falmer Brighton BN1 9PX, United Kingdom. k.a.miles@bsms.ac.uk

European Radiology
|July 26, 2008
PubMed
Summary
This summary is machine-generated.

CT perfusion imaging offers reproducible, validated insights into vascularity for brain and body imaging. This technique aids in diagnosing stroke, assessing tumors, and monitoring treatment response, enhancing patient care.

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Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG
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Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG

Published on: December 28, 2014

Area of Science:

  • Radiology
  • Medical Imaging
  • Vascular Physiology

Background:

  • Multidetector CT systems and analysis software enable routine CT perfusion imaging.
  • Perfusion CT is often an adjunct to conventional CT examinations.
  • Derived perfusion values are reproducible and validated against reference techniques.

Purpose of the Study:

  • To highlight the applications of CT perfusion imaging in clinical practice.
  • To demonstrate its utility in neuroradiology and oncology.
  • To emphasize its role in improving diagnosis, prognosis, and treatment monitoring.

Main Methods:

  • Utilizes contrast media to quantify contrast enhancement.
  • Exploits CT system capabilities for physiological assessment.
  • Integrates with conventional CT protocols for comprehensive evaluation.

Main Results:

  • CT perfusion imaging is valuable for assessing acute stroke and secondary head trauma injuries.
  • It aids in evaluating cerebral spasm in subarachnoid hemorrhage.
  • In oncology, it differentiates lesions, indicates aggressiveness, reveals occult tumors, and aids radiotherapy planning.

Conclusions:

  • CT perfusion imaging provides functional assessment of tumor vascularity and response to therapy.
  • It improves tumor delineation for radiotherapy planning.
  • The technique enhances diagnosis, prognosis, treatment selection, and therapy monitoring through vascular physiology assessment.