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NK receptor interactions with MHC class I molecules in pregnancy

John Trowsdale1, Ashley Moffett

  • 1Immunology Division, Department of Pathology, Tennis Court Road, Cambridge CB2 1QP, United Kingdom.

Seminars in Immunology
|July 29, 2008
PubMed
Summary

Polymorphisms in human leukocyte antigen (HLA) class I and killer cell immunoglobulin-like receptor (KIR) genes may influence pregnancy outcomes. The maternal KIR and fetal HLA-C interaction impacts fetal development and reproductive success.

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