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Antibiotic use in post-adenotonsillectomy morbidity: a randomized prospective study
Marja Michelin Guerra1, Eduardo Garcia, Renata Ribeiro de Mendonça Pilan
1FMABC, Brazil.
Insights
Post-tonsillectomy recovery was not improved by a 7-day course of amoxicillin. This study found no significant benefits in pain, intake, or fever when comparing antibiotic use to analgesics alone in pediatric patients.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Pharmacology
Background:
- Tonsillectomy and adenoidectomy are common procedures, especially in children.
- Postoperative recovery can involve pain, nausea, and delayed return to normal activities.
Purpose of the Study:
- To evaluate the effect of a 7-day course of amoxicillin on recovery after tonsillectomy with or without adenoidectomy.
- To compare outcomes in patients receiving amoxicillin plus analgesics versus analgesics alone.
Main Methods:
- A prospective, randomized, controlled study involving 120 pediatric patients.
- Patients received either 7 days of amoxicillin with pain relief or pain relief alone post-surgery.
- Outcomes assessed included pain, oral intake, nausea, vomiting, fever, and return to daily activities within the first postoperative week.
Main Results:
- A statistically significant difference in pain levels was observed only on the fourth postoperative day in favor of the antibiotic group.
- No significant differences were found between the groups regarding oral intake, nausea, vomiting, fever, or return to daily activities.
Conclusions:
- A 7-day postoperative course of amoxicillin does not appear to improve patient recovery after tonsillectomy/adenoidectomy.
- The findings suggest that routine antibiotic use in the postoperative period may not be beneficial for typical recovery metrics.
Unlabelled:
Tonsillectomy with or without adenoidectomy still is one of the most commonly performed surgical procedures in the world, mostly in the pediatric population.
Aim:
to study the impact of amoxicillin for 7 days in post-adenotonsillectomy recovery, comparing results with a control group.
Study Type:
prospective, randomized, controlled study with 120 patients.
Patients And Methods:
the patients were randomized according to surgery time to receive 7 days of amoxicillin associated with pain killers, or analgesic alone. During the first week of postoperative, we assessed the level of pain, oral intake acceptance, nausea and vomits, fever and return to daily activities.
Results:
It was only in the fourth post-operative day that the group receiving antibiotic agents showed a statistically significant difference as far as pain is concerned. There was no difference between the two groups for other data analyzed.
Conclusion:
considering the results from our study and reviewing the literature on the use of antibiotic agents, we agree that there is no improvement in patient recovery after adenotonsillectomy with the use of amoxicillin for 7 days in the postoperative.
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