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[Study on antioxidant activity of constituents from mulberry leaf]
Yu-Lan Jiang1, Hui-Shan Piao, Gao Li
1College of Preclinical Medicine, Yanbian University, Yanji 133000, China.
Objective:
To study the chemical constituents with antioxidant activity from mulberry leaf.
Methods:
Siliga gel column chromatography was used to isolate, and their structures were identified by spectras.
Methods:
Isolated constituents were tested in vitro for antioxidant activity against 1, 1-diphenyl -2-picrylhydrazyl (DPPH) and 2, 2' -azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS+) radicals.
Results:
Four known flavonoids were isolated from mulberry leaf and their structures were identified as kaempferol-3-O-beta-D-glucopyranoside (I), quercetin-3-O-beta-D-glucopyranoside (II), quercitrin (III), morin-3-O-beta-D-glucopyranoside (IV). All these compounds showed DPPH and ABTS+ radicals scavenging activity.
Conclusion:
Compound IV has the strongest ABTS+ radicals scavenging effects.
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