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[Chemical constituents from sea cucumber Holothuria nobilis]
Jia-Jia Zhang1, Jing-Bo Dai, Li-Li Chen
1Zhejiang Pharmaceutical College, Ningbo 315200, China. zjj@zjbti.net.cn
Objective:
To study the chemical constituents of sea cucumber Holothuria hilla L..
Methods:
Compounds were isolated from the sea cucumber by multi-chromatography on Si gel, ODS Rp C-18 gel, DA101 resin, Sephadex LH-20 and HPLC. The structures were elucidated according to their spectral data and chemical character.
Results:
Four compounds were isolated from the sea cucumber, and were identified as: holothuria A (I), thymine (II), uracil (III), cholesterol (IV).
Conclusion:
Compounds I IV are obtained from this kind of sea cucumber for the first time.
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