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Evaluation of T Follicular Helper Cells and Germinal Center Response During Influenza A Virus Infection in Mice
Published on: June 27, 2020
[Effects of Qiulirunfei extracta on immunological function and influenza virus in mice]
1Department of Microbiology of Tianjin Medical University, Tianjin 300070, China.
Objective:
To investigate the effect of Qiulirunfei extracta on immunological function and Influenza virus type A (FM1 strain) in ICR mice.
Methods:
After given Qiulirunfei extracta, mice's body weight, spleen weight and lymphocyte stimulation index (SI) were tested; its antiviral effect was also observed in mice and chick embryo.
Results:
Qiulirunfei extracta inhibited effectively the growth of influenza virus type A (FM1 strain) in chick embryo, and reduced the mortality rate of mice infected by influenza virus type A (FM1 strain). Compared with control group, body weight, spleen index in experiment group increased greatly, and SI of lymphocyte increased significantly too.
Conclusion:
Qiulirunfei extracta shows antiviral effects, and it is a good immune system enhancer.
