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Published on: December 22, 2023
[Study on effect of demethoxycurcumin in Curcuma long on stability of curcumin]
1Tangshan Key Laboratory of New Drug Research, Pharmaceutical Department of North China Coal Medical College, Tangshan 063000, China. tsyxhg@163.com
Objective:
To investigate effect of demethoxycurcumin on stability of curcumin.
Methods:
To add the demethoxycurcumin to pure curcumin, the change of curcumin was determined by HPLC and the dynamics of curcumin degradation was investigated.
Result:
The stability both obtained from alcohol and demethoxycurcumin improved the stabilization of curcumin, the demi-period of curcumin prolonged with the addition of demethoxycurcumin.
Conclusion:
The commixture of curcumin and demethoxycurcumin are more stable than pure curcumin at the same conditions. Stability of curcumin is improved by demethoxycurcumin,it is crude stabilizing agent.
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