Related Experiment Video
Updated: Jul 3, 2026

Quail Chorioallantoic Membrane - A Tool for Photodynamic Diagnosis and Therapy
Published on: April 28, 2022
Chick chorioallantoic membrane as an in situ biological membrane for pharmaceutical formulation development: a review
Constance L L Saw1, Paul W S Heng, Celine V Liew
1Department of Pharmacy, National University of Singapore, Singapore.
Abstract:
The use of animals in research has always been a debatable issue. Over the past few decades, efforts have been made to reduce, replace, and refine experiments for ethical use of experimental animals. The use of chick chorioallantoic membrane (CAM) was one of the proposed alternatives to the Draize rabbit ocular irritation test with several advantages including simplicity, rapidity, sensitivity, ease of performance, and cost-effectiveness. The recent use of CAM in the development of pharmaceuticals and testing models to mimic human tissue, including drug transport across CAM, will be discussed in this review.
Related Concept Videos
Membrane Fluidity
Asymmetric Lipid Bilayer
Synthesis of Phosphatidylcholine in the ER Membrane
The major components of all eukaryotic cell...
Assembly of the Lipid Bilayer in the ER
A large chunk of any biological membrane is composed of phospholipids. These lipids have a heterogeneous distribution across different subcellular organelles and even between...

