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Updated: Jul 3, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
ent-kaurane diterpenoids from the liverwort Jungermannia atrobrunnea
Jian-Bo Qu1, Rui-Liang Zhu, Yan-Li Zhang
1Department of Natural Products Chemistry, School of Pharmaceutical Sciences, Shandong University, No. 44 West Wenhua Road, Jinan 250012, People's Republic of China.
Abstract:
Three new rearranged ent-kaurane-type diterpenoids (1-3) and seven new ent-kaurane-type diterpenoids (4-10) have been isolated from the liverwort Jungermannia atrobrunnea. Their structures were determined by extensive spectroscopic techniques and X-ray crystallographic analysis. The absolute configurations of these compounds were clarified by CD spectroscopic studies. Compound 1 is the first example of a rearranged ent-kaurane diterpenoid possessing a peroxide bridge.
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