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[The dry eye syndrome in children with juvenile idiopatic arthritis]

Ewa Lipiec1, Mirosława Grałek, Anna Niwald

  • 1Z Kliniki Okulistyki Dzieciecej Katedry Pediatrii Zabiegowej Uniwersytetu Medycznego w Lodzi.

Klinika Oczna
|August 2, 2008
PubMed

Insights

Children with juvenile idiopathic arthritis (JIA) frequently experience dry eye syndrome, impacting their quality of life. This study found no correlation between JIA immunological markers and ocular symptoms in pediatric patients.

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Pediatrics

Context:

  • Juvenile idiopathic arthritis (JIA) is a chronic autoimmune disease affecting children.
  • Ocular complications, including dry eye syndrome, can occur in JIA patients.
  • The relationship between JIA, its immunological markers, and dry eye syndrome in children requires further investigation.

Purpose:

  • To evaluate the prevalence of dry eye syndrome in children diagnosed with JIA.
  • To assess the association between dry eye syndrome and specific immunological markers (antinuclear antibodies [ANA] and rheumatoid factor [RF]) in pediatric JIA patients.
  • To determine the impact of dry eye syndrome on the quality of life for children with JIA.

Summary:

  • This study included 62 children with JIA and 49 healthy controls, observing them over 18 months.
  • Ophthalmic examinations, including Schirmer and tear breakup time (BUT) tests, identified dry eye syndrome in 17.7% of JIA patients.
  • Subjective eye discomfort was significantly higher in the JIA group compared to controls, despite a lack of correlation with ANA or RF levels.

Impact:

  • Dry eye syndrome is a common, often subclinical, finding in children with JIA, negatively affecting their quality of life.
  • The study highlights the need for routine ophthalmic screening in pediatric JIA patients to detect and manage dry eye.
  • Current immunological markers for JIA do not appear to predict the presence or severity of ocular surface disease.
Abstract

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