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Updated: Jul 3, 2026

06:46
Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
Published on: January 16, 2013
[Etiotropic therapy of chronic bacterial prostatitis]
Urologiia (Moscow, Russia : 1999)
|August 2, 2008
Summary
Russian-produced levofloxacin (floracid) effectively treated chronic bacterial prostatitis in 90% of patients. The drug demonstrated good safety and improved patient quality of life with no reported side effects.
Area of Science:
- Urology
- Infectious Diseases
- Pharmacology
Context:
- Chronic bacterial prostatitis (CBP) presents a persistent clinical challenge requiring effective antimicrobial therapy.
- Assessing novel therapeutic options for CBP is crucial for improving patient outcomes.
- Russian-produced levofloxacin (floracid) is a potential treatment for CBP.
Purpose:
- To evaluate the efficacy and safety of Russian-produced levofloxacin (floracid) in patients with chronic bacterial prostatitis.
- To determine the microbiological eradication rates of levofloxacin in CBP patients.
- To assess the impact of levofloxacin on CBP symptoms and quality of life.
Summary:
- A clinical trial involving 20 patients with chronic bacterial prostatitis (CBP) investigated the efficacy and safety of levofloxacin (floracid) at 500 mg/day for 28 days.
- Antibacterial treatment with floracid resulted in the eradication of susceptible bacteria in 18 out of 20 (90%) patients.
- Significant improvements were observed in disease symptoms, including pain and voiding disorders, with enhanced quality of life as measured by the NIH-CPSI scale.
Impact:
- Levofloxacin (floracid) demonstrates high efficacy in treating chronic bacterial prostatitis.
- The drug is well-tolerated, with no observed side effects, indicating a favorable safety profile.
- Improved clinical outcomes and quality of life suggest levofloxacin is a valuable therapeutic option for CBP.
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