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Updated: Jul 3, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
[Aspergillosis]
Patrice Bourée1, Francine Bisaro
1Unité des maladies parasitaires et tropicales, hôpital Bicêtre, AP-HP, 94275 Kremlin-Bicêtre. patrice.bouree@bct.aphp.fr
Abstract:
Aspergillosis, due to moulds belonging to the genus Aspergillus, occurs in patients with residual lung cavities. The clinical manifestations are determined by the host immune response, ranging from a local inflammatory response to the systemic dissemination. Haemoptysis is the most common symptom. The chest X-ray reveals a round mass with a radio-lucent crescent of air. The antifungal treatments are successful.
Insights
Aspergillosis, a fungal infection caused by Aspergillus, affects individuals with lung cavities. Treatment with antifungal medications is effective for managing this condition.
Area of Science:
- Medical Mycology
- Pulmonology
Background:
- Aspergillosis is a fungal infection caused by Aspergillus molds.
- It commonly affects patients with pre-existing lung cavities.
Purpose of the Study:
- To describe the clinical presentation and diagnosis of aspergillosis.
- To highlight the effectiveness of antifungal treatments.
Main Methods:
- Review of clinical manifestations.
- Radiological findings (chest X-ray).
- Treatment outcomes.
Main Results:
- Haemoptysis is the most frequent symptom.
- Chest X-ray typically shows a round mass with an air crescent.
- Antifungal therapy is successful in treating the condition.
Conclusions:
- Aspergillosis in patients with lung cavities presents with characteristic symptoms and radiological signs.
- Effective antifungal treatments are available.
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