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Updated: Jul 3, 2026

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei
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An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei

Published on: February 17, 2014

Preclinical study of new TB drugs and drug combinations in mouse models

Boris V Nikonenko1, Katherine A Sacksteder, Sam Hundert

  • 1Sequella, Inc., 9610 Medical Center Drive, Suite 200, Rockville, MD 20850, USA. borisnikonenko@sequella.com

Recent Patents on Anti-Infective Drug Discovery
|August 5, 2008
PubMed

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...