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Updated: Jul 3, 2026
A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Comparison of incidence and angiography patterns in definite thrombosis between drug-eluting and bare-metal stents
Insights
Stent thrombosis, a serious complication of percutaneous coronary intervention, occurred similarly in patients receiving drug-eluting or bare-metal stents. Late stent thrombosis was rare but more frequent with drug-eluting stents.
Area of Science:
- Cardiology
- Interventional Cardiology
- Biomedical Engineering
Background:
- Stent thrombosis is a critical complication following percutaneous coronary intervention (PCI).
- Understanding the comparative incidence of thrombosis between different stent types is crucial for patient outcomes.
Purpose of the Study:
- To analyze the incidence of angiographically-confirmed stent thrombosis in patients treated with drug-eluting stents (DES) versus bare-metal stents (BMS).
Main Methods:
- A retrospective analysis of 5011 consecutive patients undergoing PCI with either DES or BMS.
- Assessment of angiographically-confirmed stent thrombosis incidence and timing.
Main Results:
- The overall incidence of stent thrombosis was 0.8% in both DES and BMS groups.
- Angiographically-documented late stent thrombosis was infrequent but occurred more often with DES (0.25%) compared to BMS (0.06%, P=.03).
Conclusions:
- While overall stent thrombosis rates are similar, late thrombosis is a rare but notable concern with DES.
- Further research into mitigating late thrombosis risk with DES is warranted.
Abstract:
Stent thrombosis is a feared complication of percutaneous coronary intervention due to its catastrophic consequences. We analysed the incidence of angiographically-confirmed thrombosis in 5011 consecutive patients treated with drug-eluting stents or bare-metal stents. Although the incidence of thrombosis was similar between the two groups (0.8%), angiographically-documented late thrombosis was a relatively unusual complication after implantation of either stent, though it was more common with drug-eluting stents than bare-metal stents (0.25 vs. 0.06%, P=.03).