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High Yield Purification of Plasmodium falciparum Merozoites For Use in Opsonizing Antibody Assays
Published on: July 17, 2014
Malaria vaccines: immunity, models and monoclonal antibodies
1Centre for Medical Parasitology at the Department for International Health, Immunology, and Microbiology (ISIM), University of Copenhagen, 1014 Copenhagen K, Denmark. lhcmp@rh.dk
Abstract:
Although experts in the field have agreed on the malaria vaccine technology roadmap that should be followed (http://www.malariavaccineroadmap.net/), the path towards an effective malaria vaccine remains littered with intellectual and practical pot-holes. The animal models that are currently available are problematic, and current understanding of the exact mechanisms and targets of protective immune responses is incomplete. However, recent technological advances might help overcome some of these hurdles.
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