Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's phenomenon, is a...
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
Hormonal Regulation of Blood Pressure01:17

Hormonal Regulation of Blood Pressure

Endocrinal or hormonal intervention in the cardiovascular system is predominantly exerted by the catecholamines - epinephrine and norepinephrine, as well as a slew of hormones that interact with renal function to modulate blood volume.
Epinephrine and Norepinephrine
The adrenal medulla releases epinephrine and norepinephrine, catecholamines that enhance and extend the sympathetic or "fight or flight" physiological response. These hormones escalate heart rate and the force of contraction while...
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
Neural Regulation of Blood Pressure01:18

Neural Regulation of Blood Pressure

The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
Antihypertensive Drugs: Action of β1 Blockers01:17

Antihypertensive Drugs: Action of β1 Blockers

β1-receptors are primarily located in the heart and kidneys. In cardiac myocytes, these receptors interact with neurotransmitters released by the sympathetic nervous system during heightened activity or danger. As a result, β1-receptors get activated, initiating a series of biochemical processes. Excessive activation of beta receptors due to chronic stress can abnormally increase heart rate and contractility, resulting in high blood pressure or hypertension. To counteract this, β1-blockers...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mounier-Kuhn syndrome: a typical case including CT and bronchoscopic imaging.

Oxford medical case reports·2023
Same author

[Miliary tuberculosis].

Revue de pneumologie clinique·2017
Same author

[The primary pulmonary Malt lymphoma: About a case].

Revue de pneumologie clinique·2017
Same author

[Tuberculosis of the lung bases].

Revue de pneumologie clinique·2016
Same author

[Treatment of the first episode of spontaneous pneumothorax].

Revue des maladies respiratoires·2016
Same author

[Silicotuberculosis].

Revue de pneumologie clinique·2016

Related Experiment Video

Updated: Jul 3, 2026

Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats
06:30

Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats

Published on: September 11, 2018

[Sympathetic response in primary hypertension].

H Benjelloun1, S Aboudrar, I Jroundi

  • 1Service de Cardiologie A, CHU Ibn Sina, Rabat, Morocco. benjellounhalima@hotmail.com

Annales De Cardiologie Et D'Angeiologie
|August 6, 2008
PubMed
Summary
This summary is machine-generated.

Primary hypertension is linked to increased sympathetic nervous system activity and reduced parasympathetic function. This study found hypertensive patients exhibit heightened sympathetic responses and diminished parasympathetic responses compared to healthy individuals.

Related Experiment Videos

Last Updated: Jul 3, 2026

Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats
06:30

Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats

Published on: September 11, 2018

Area of Science:

  • Cardiology
  • Autonomic Neuroscience
  • Hypertension Research

Context:

  • Primary hypertension is a prevalent condition associated with cardiovascular disease.
  • Sympathetic nervous system hyperactivity is a potential contributing factor in hypertension.
  • Understanding autonomic dysfunction in hypertension is crucial for risk stratification.

Purpose:

  • To evaluate sympathetic nervous system activity in patients with primary hypertension.
  • To compare cardiovascular autonomic function between hypertensive and normotensive individuals.
  • To assess autonomic responses using deep-breathing, hand-grip, and echostress tests.

Summary:

  • Hypertensive patients (n=120) and normotensive controls (n=120) underwent autonomic function testing.
  • Significant differences were observed in sympathetic responses to echostress and hand-grip tests.
  • Hypertensive individuals showed reduced parasympathetic response during deep-breathing and hand-grip tests compared to controls.

Impact:

  • Findings suggest a hyperactive sympathetic system and hypoactive parasympathetic system in primary hypertension.
  • This research highlights the role of autonomic imbalance in the pathophysiology of hypertension.
  • Results may inform the development of targeted therapeutic strategies for hypertension management.