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Updated: Mar 22, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
[Tuberculosis of the lung bases]
I Elkard1, N Zaghba1, H Benjelloun1
1Service des maladies respiratoires, CHU Ibn Rochd, Casablanca, Maroc.
Basal pulmonary tuberculosis is a rare condition in Morocco, often leading to diagnostic delays. Early consideration in patients with comorbidities is crucial for timely treatment and improved outcomes.
Area of Science:
- Pulmonology
- Infectious Diseases
- Radiology
Background:
- Tuberculosis (TB) poses a significant public health challenge in Morocco.
- Basal pulmonary tuberculosis is an uncommon and atypical manifestation, presenting diagnostic difficulties.
Purpose of the Study:
- To describe the clinical, radiological, and microbiological characteristics of basal pulmonary tuberculosis.
- To highlight the diagnostic challenges and emphasize the importance of considering this atypical TB form.
Main Methods:
- A retrospective study of 21 cases of basal pulmonary tuberculosis.
- Data collected from Ibn Rushd hospital in Casablanca between 2004 and 2015.
- Analysis of patient demographics, diagnostic timelines, radiological findings, comorbidities, bronchoscopic results, and microbiological data.
Main Results:
- The majority of patients (62%) were women, with an average age of 33 years.
- Diagnosis averaged 25 days; the disease was predominantly unilateral (95%), affecting the right lower lobe most frequently (71%).
- Common radiological findings included inhomogeneous opacities (66%), with diabetes being the most frequent comorbidity (28%). Microbiological confirmation varied across sample types.
Conclusions:
- Basal pulmonary tuberculosis presents misleading features, contributing to diagnostic delays.
- Increased awareness and consideration of basal pulmonary tuberculosis are essential, particularly in patients with comorbidities.
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