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Updated: Jul 3, 2026

Influenza Virus Propagation in Embryonated Chicken Eggs
Published on: March 19, 2015
Early pathogenesis of experimental reovirus infection in chickens
R C Jones1, M R Islam, D F Kelly
1Department of Veterinary Pathology, University of Liverpool, Neston, Wirral, England.
Abstract:
One-day-old specific-pathogen-free, light hybrid chickens were infected orally with an avian arthrotropic reovirus and examined at intervals from 2 h until 12 days after infection. Entry, primary replication and spread of virus were studied by infectivity assay, immunohistochemical study and electron microscopy in a wide range of tissues. These showed viral entry and primary replication in the epithelium of intestine and bursa of Fabricius within 12 h after oral infection. These were followed by a rapid and pantropic distribution of virus which reached most tissues within 24 to 48 h after infection.
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