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Updated: Jun 21, 2026
08:01
Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal
Published on: May 30, 2012
TGFbeta and SMADs talk to NANOG in human embryonic stem cells
1Gene Regulation Laboratory, Genome Institute of Singapore, Singapore 138672, Republic of Singapore.
Cell Stem Cell
|August 7, 2008
Abstract:
The TGFbeta/activin signaling pathway is important for the maintenance of human embryonic stem cells. In this issue of Cell Stem Cell, Xu et al. (2008) show that this pathway upregulates the expression of a key pluripotency gene NANOG through SMAD2/3.
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