Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Robotic segmental ureterectomy for upper tract urothelial carcinoma: comparable short-term oncological outcomes and improved postoperative recovery compared to open approach.

World journal of surgical oncology·2026
Same author

Endoscopic management of ureteral injuries arising from gynecologic procedures.

BJUI compass·2026
Same author

Multidisciplinary protocol and outcomes in placenta accreta spectrum: a 12 year cohort study.

Archives of gynecology and obstetrics·2026
Same author

Optimal Timing of Percutaneous Nephrostomy Tube Drainage of Infected Kidneys Secondary to Obstructing Ureteral Stones.

Journal of endourology·2025
Same author

High-Power Retrograde Intrarenal Surgery Holmium Laser Lithotripsy for Kidney Stones Larger Than 20 mm.

Journal of endourology·2025
Same author

[ROBOT-ASSISTED PYELOLITHOTOMY IN PELVIC KIDNEY].

Harefuah·2025

Related Experiment Video

Updated: Jul 3, 2026

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

Bone imaging in prostate cancer.

Zohar A Dotan1

  • 1Department of Urology, Sheba Medical Center, Tel Hashomer 52662, Israel. zohar.dotan@sheba.health.gov.il

Nature Clinical Practice. Urology
|August 7, 2008
PubMed
Summary

Diagnosing bone metastases, especially in prostate cancer, is challenging due to similar-looking benign lesions. Advanced imaging like PET, PET-CT, and MRI offer higher sensitivity than conventional bone scans for accurate detection and patient management.

Area of Science:

  • Oncology
  • Radiology
  • Nuclear Medicine

Background:

  • Bone metastases are common in solid tumors, particularly breast, lung, and prostate cancers.
  • Diagnosis relies on radiographic evidence, with prostate cancer metastases often showing osteoblastic features.
  • Conventional bone scans have limitations, including low sensitivity and high false-negative rates, especially for low-burden disease.

Purpose of the Study:

  • To highlight the diagnostic challenges of bone metastases, especially in prostate cancer.
  • To compare the efficacy of conventional bone scans with advanced imaging modalities.
  • To emphasize the importance of accurate diagnosis for treatment assessment and patient prognosis.

Main Methods:

  • Review of conventional bone scan techniques (e.g., (99m)Tc-labeled methylene diphosphonate).

More Related Videos

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model
06:32

Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model

Published on: November 4, 2022

Related Experiment Videos

Last Updated: Jul 3, 2026

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model
06:32

Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model

Published on: November 4, 2022

  • Comparison with advanced imaging modalities: Positron Emission Tomography (PET), PET-Computed Tomography (PET-CT), and Magnetic Resonance Imaging (MRI).
  • Discussion of predictive tools like nomograms for identifying patients at risk.

    • Main Results:

    • Conventional bone scans are limited by low sensitivity and high false-negative rates (up to 40%).
    • Advanced imaging modalities (PET, PET-CT, MRI) show potential to assist or replace conventional scanning.
    • Accurate diagnosis is crucial for assessing therapy effects, prognosis, and bone-specific treatments.

    Conclusions:

    • Advanced imaging techniques are superior to conventional bone scans for detecting bone metastases.
    • Accurate diagnosis of bone involvement in prostate cancer is critical for patient management and treatment efficacy.
    • Predictive tools can help identify at-risk patients, potentially reducing costs and complications.