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Updated: Jul 3, 2026
10:44
Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Smoking cessation therapy with varenicline
Uma M Mohanasundaram1, Rajinder Chitkara, Ganesh Krishna
1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Stanford University School of Medicine, CA, USA.
Summary
Smoking cessation is crucial for managing chronic obstructive pulmonary disease (COPD). Varenicline, a new medication, effectively reduces cravings and withdrawal symptoms, aiding smoking cessation efforts.
Area of Science:
- Pulmonology
- Pharmacology
- Addiction Medicine
Background:
- Chronic obstructive pulmonary disease (COPD) progression is halted solely by smoking cessation.
- Current smoking cessation methods have varying success rates.
Purpose of the Study:
- To review existing smoking cessation treatments.
- To evaluate the efficacy and role of varenicline in smoking cessation for COPD patients.
Main Methods:
- Literature review of smoking cessation therapies.
- Analysis of studies on varenicline's efficacy and tolerability.
Main Results:
- Varenicline is a novel partial nicotinic acetylcholine receptor agonist.
- It exhibits both agonistic and antagonistic properties, reducing craving and withdrawal while blocking smoking's rewarding effects.
- Varenicline demonstrates improved efficacy and tolerability compared to other options.
Conclusions:
- Varenicline is a valuable therapeutic option for smoking cessation in COPD.
- Its targeted mechanism and favorable profile support its use in clinical practice.
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