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Polypharmacy: misleading, but manageable.

Reamer L Bushardt1, Emily B Massey, Temple W Simpson

  • 1Department of Clinical Services, Medical University of South Carolina, Charleston, South Carolina, USA. busharrl@musc.edu

Clinical Interventions in Aging
|August 9, 2008
PubMed
Summary
This summary is machine-generated.

Polypharmacy, the use of multiple medications, affects a significant percentage of elderly patients. This study highlights the need for clear definitions and tools to manage medication risks in older adults.

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Area of Science:

  • Gerontology
  • Clinical Pharmacy
  • Public Health

Background:

  • The aging population presents challenges in managing multiple chronic diseases concurrently.
  • Polypharmacy (multiple medication use) in the elderly increases risks like adverse effects and drug interactions.

Purpose of the Study:

  • To establish a consensus definition for polypharmacy.
  • To assess the prevalence of polypharmacy in elderly outpatients.
  • To identify or develop a clinical tool for managing inappropriate drug therapy in the elderly.

Main Methods:

  • Reviewed common definitions of polypharmacy, noting frequent use of 'medication not matching a diagnosis' and 'inappropriate'.
  • Evaluated polypharmacy using two definitions (≥6 medications or potentially inappropriate medication) in 1027 elderly South Carolinians.

Main Results:

  • 29.4% of elderly patients were prescribed six or more concurrent drugs.
  • 15.7% were prescribed at least one potentially inappropriate medication.
  • 9.3% met both defined criteria for polypharmacy.

Conclusions:

  • A significant portion of the elderly population experiences polypharmacy.
  • Recommended clearer terminology like 'hyperpharmacotherapy' or 'multiple medication use'.
  • Suggested a structured approach and provided a clinical tool to manage inappropriate polypharmacy.