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Psychosurgery

Psychosurgery

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Related Experiment Video

Updated: Jul 3, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Hemispherotomy for intractable epilepsy.

Poodipedi Sarat Chandra¹, Vasantha M Padma, Gaikwad Shailesh

¹Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.

Neurology India

|August 9, 2008

Summary

This summary is machine-generated.

Hemispherotomy surgery effectively treats intractable epilepsies, with both vertical parasagittal and peri-insular techniques yielding excellent seizure control. Cognitive function improved significantly in most patients post-surgery.

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Last Updated: Jul 3, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Published on: August 16, 2024

Area of Science:

Neurosurgery
Epileptology
Pediatric Neurology

Background:

Hemispherotomy is a complex surgical disconnection for treating severe epilepsy.
This study presents institutional experience with hemispherotomy procedures.

Purpose of the Study:

To compare the efficacy of two hemispherotomy techniques in patients with intractable epilepsies.
To validate the effectiveness of hemispherotomy for drug-resistant epilepsy.

Main Methods:

Retrospective analysis of 19 hemispherotomy cases (2001-2007) from 462 epilepsy surgeries.
Patients aged 4-23 with diverse pathologies including Rasmussen's and hemimegalencephaly.
Surgical techniques included vertical parasagittal and peri-insular approaches; neuronavigation used in 7 cases.

Main Results:

Excellent seizure control (Engel Class I) achieved in 18 of 19 patients.
Significant cognitive improvement observed in all patients, with 11 returning to school.
Transient postoperative weakness occurred in 4 patients, with most recovering to baseline or improved function.

Conclusions:

Both vertical parasagittal and peri-insular hemispherotomy techniques are highly effective for intractable epilepsy.
Hemispherotomy is a beneficial procedure when indicated, even in critically ill patients.
The surgery leads to significant seizure reduction and cognitive enhancement.