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Updated: Jul 3, 2026

Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
Published on: July 6, 2016
Design, synthesis and DNA-cleaving efficiency of photoswitchable dimeric azobenzene-based C2-symmetric enediynes
Amit Basak1, Debarati Mitra, Moumita Kar
1Bioorganic Laboratory, Department of Chemistry, Indian Institute of Technology, Kharagpur, India. absk@chem.iitkgp.ernet.in
Abstract:
Designed azobenzene-based enediyne-amino acid C(2)-symmetric hybrids have been synthesized and the role of amino acid linker in stabilizing the Z form has been demonstrated; DNA-binding and cleavage studies have established higher reactivity of the Z-isomers.
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