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Updated: Jul 3, 2026
10:37
Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
Published on: November 30, 2016
[Diarrhea predominant irritable bowel syndrome]
Jean-Marc Sabaté1, Benoît Coffin
1Service d'hepato-gastroentŕologie, Hôpital Louis-Mourier, AP-HP 92700 Colombes, France.
La Revue Du Praticien
|August 12, 2008
Summary
Diarrhea-predominant irritable bowel syndrome (D-IBS) requires a positive diagnosis using Rome criteria, not exclusion. Unnecessary investigations often yield normal results, impacting symptom evolution.
Area of Science:
- Gastroenterology
- Functional Gastrointestinal Disorders
Context:
- Diarrhea-predominant irritable bowel syndrome (D-IBS) diagnosis is often made through exclusion.
- Investigations are frequently performed despite normal expected results.
Purpose:
- To emphasize the importance of a positive diagnosis for D-IBS based on Rome criteria.
- To highlight that extensive investigations are often unnecessary and do not influence symptom progression.
Summary:
- D-IBS diagnosis should be positive, adhering to Rome criteria.
- Systematic, exhaustive investigations are not systematically required for D-IBS.
- Normal investigation results do not positively influence symptom evolution in D-IBS.
Impact:
- Promotes accurate D-IBS diagnosis, reducing unnecessary medical testing.
- Guides clinical practice towards evidence-based diagnostic and treatment strategies for D-IBS.
- Potential to decrease healthcare costs associated with superfluous investigations.
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