Related Experiment Video
Updated: Jul 2, 2026

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
Published on: January 31, 2022
Liver enzymes in Nigerians with lichen planus
O O M Daramola1, F A Abbiyesuku, J A Otegbayo
1Department of Medicine, University of Ilorin, Ilorin. nikem95@yahoo.com
Introduction:
Lichen planus has been reported in association with liver diseases. Clinical signs such as jaundice may not be reliable indicator of ongoing inflammation or the presence of an ongoing liver disease. Liver function test in spite of its variability may serve as a more reliable indicator of liver disease. The objective of this study is to assess the discriminant power of liver enzymes with lichen planus and control.
Methods:
Sixty Nigerians with lichen planus (LP group) and 30 patients with other dermatoses control group A) and 30 apparently normal individual (control group B) had their liver enzymes assayed using the automated Hitachi 70 auto-analyzer.
Result:
There was no a statistically significant difference in the level of liver enzymes between the LP group and controls.
Conclusion:
Liver enzymes in Nigerian with lichenplanus are generally within normal limits and are comparable to individuals without lichen planus.
Related Concept Videos
Jaundice
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
Pharmacogenetics of Phase II Enzymes: N-acetyltransferase, Thiopurine S-methyltransferase, UDP-glucuronosyltransferase
Antiprotozoal Agents
Liver Regeneration
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are large...
Liver Histology
Hepatocytes perform a variety of essential functions. They secrete...