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Obesity and persisting sleep apnea after adenotonsillectomy in Greek children
Maria T Apostolidou1, Emmanouel I Alexopoulos2, Konstantinos Chaidas2
1Department of Otorhinolaryngology, University of Thessaly School of Medicine, Larissa, Greece.
Insights
Adenotonsillectomy (AT) effectively treats sleep-disordered breathing (SDB) in children, regardless of obesity. This study found no significant difference in SDB cure rates between obese and nonobese children after AT.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Pediatric Pulmonology
Background:
- The role of obesity versus adenotonsillar hypertrophy in childhood obstructive sleep-disordered breathing (SDB) is not fully understood.
- Adenotonsillectomy (AT) is a common treatment for SDB, but its success rates can vary, particularly in obese children who may have residual disease postoperatively.
Purpose of the Study:
- To evaluate the effectiveness of adenotonsillectomy (AT) as a treatment for sleep-disordered breathing (SDB) in both obese and nonobese children.
Main Methods:
- Children with adenoidal/tonsillar hypertrophy undergoing AT for SDB had pre- and post-operative polysomnography.
- Obesity was defined as a body mass index (BMI) z score > 1.645.
- The primary outcome was the cure of SDB, defined as a postoperative obstructive apnea-hypopnea index (OAHI) < 1 episode/hour.
Main Results:
- The study included 22 obese and 48 nonobese children.
- Post-AT, the cure rates for SDB did not significantly differ between obese (22.7%) and nonobese (25%) children (p > 0.05).
- Obesity, hypertrophy type, gender, and postoperative BMI changes were not significant predictors of SDB cure.
Conclusions:
- Adenotonsillectomy (AT) demonstrates comparable efficacy in treating sleep-disordered breathing (SDB) in both obese and nonobese pediatric populations.
- Obesity is not a predictor of poor outcomes following AT for SDB in children.
Background:
The relative importance of obesity and adenotonsillar hypertrophy in the pathogenesis of obstructive sleep-disordered breathing (SDB) in childhood is unclear. Adenotonsillectomy (AT) for SDB is not always curative, and obese children are at increased risk for residual disease postoperatively.
Objective:
The aim of this investigation was to assess the efficacy of AT as treatment for SDB in obese and nonobese children.
Methods:
Children with adenoidal and/or tonsillar hypertrophy who underwent AT for the treatment of SDB underwent polysomnography preoperatively and postoperatively. A body mass index (BMI) z score of > 1.645 was used to define obesity. The achievement of a postoperative obstructive apnea-hypopnea index (OAHI) of less than one episode per hour (ie, the cure of SDB) was the primary outcome measure.
Results:
Twenty-two obese children (mean [+/- SD] age, 5.8 +/- 1.8 years; mean BMI z score, 2.6 +/- 0.8; mean OAHI, 9.5 +/- 9.7 episodes per hour) and 48 nonobese children (mean age, 6.9 +/- 2.6 years; mean BMI z score, 0.09 +/- 1.1; OAHI, 6 +/- 5.4 episodes per hour) were recruited. After surgery, obese and nonobese subjects did not differ in the efficacy of AT (postoperative OAHI of less than one episode per hour, 22.7% vs 25% of subjects, respectively; p > 0.05). The presence of obesity, adenoidal or tonsillar hypertrophy, gender, and postoperative BMI change were not significant predictors of SDB cure.
Conclusions:
Obesity does not necessarily predict an unfavorable outcome of AT as treatment for SDB.
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