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Multifocality as a prognostic factor in breast cancer patients registered in Danish Breast Cancer Cooperative Group
L E Joergensen1, K A Gunnarsdottir, C Lanng
1Danish Breast Cancer Cooperative Group, Section 2501, Blegdamsvej 9, DK-2100 KBH Ø, Denmark. aseigneurin@chu-grenoble.fr
Abstract:
The purpose of this study was to investigate the prognostic influence of multifocality in breast cancer patients. In a cohort of 7196 patients there were 945 patients with multifocality. We found no prognostic influence of multifocality on overall survival when controlling for known prognostic factors. We found a small but significant influence on disease-free survival (HR=1.16 [1.03-1.31]) and a strong correlation between multifocality and known prognostic factors. This was in accordance with an earlier study done on a smaller population and in a different period of time [Pedersen L, Gunnarsdottir KA, Rasmussen BB, Moeller S, Lanng C. The prognostic influence of multifocality in breast cancer patients. Breast 2004;13:188-193].
