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Updated: Jul 2, 2026

The Nematode Caenorhabditis Elegans - A Versatile In Vivo Model to Study Host-microbe Interactions
Published on: October 18, 2017
An ungracious host for an unwelcome guest
Kelly J Perkins1, Nicholas J Proudfoot
1Sir William Dunn School of Pathology, South Parks Road, University of Oxford OX1 3RE, UK. kelly.perkins@path.ox.ac.uk
Abstract:
Persistence of latently infected CD4(+) T cell "reservoirs" presents a major obstacle for current HIV-1 antiretroviral therapies. In Cell Host & Microbe, two separate studies use model systems of latent infection to dissect the influence of host genes on HIV-1 transcription, yielding intriguing, though partially contradictory, conclusions.
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