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Concomitant coronary artery disease among Asian ischaemic stroke patients

Deidre Anne De Silva1, Fung Peng Woon, Kyaw Thu Moe

  • 1Singapore General Hospital campus, National University of Singapore, Singapore. deidre.a.de.silva@sgh.com.sg

Annals of the Academy of Medicine, Singapore
|August 13, 2008
PubMed

Insights

Coronary artery disease (CAD) affects 24% of ischemic stroke patients in Singapore. Key risk factors include older age, hypertension, diabetes, and South Asian ethnicity, highlighting the need for targeted prevention strategies.

Area of Science:

  • Cardiology
  • Neurology
  • Public Health

Background:

  • Coronary artery disease (CAD) is a major cause of mortality post-ischemic stroke.
  • Understanding CAD prevalence in stroke patients is crucial for effective management.

Purpose of the Study:

  • To determine the prevalence of concomitant coronary artery disease (CAD) in ischemic stroke patients.
  • To identify factors associated with CAD in this patient cohort.

Main Methods:

  • Prospective study of 2686 consecutive Asian ischemic stroke patients.
  • Analysis of demographic, clinical, and ethnic factors associated with CAD.

Main Results:

  • Prevalence of CAD was 24% among the studied ischemic stroke patients.
  • Independent associations with CAD included older age, hypertension, diabetes, hyperlipidaemia, atrial fibrillation, large stroke, and South Asian ethnicity.

Conclusions:

  • Identified CAD associations are established atherosclerotic risk factors or indicators of cardioembolic stroke.
  • The high prevalence of CAD in South Asian patients underscores ethnic disparities in cardiovascular risk.
Abstract

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