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Updated: Jul 2, 2026

05:17
Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
Synthesis and biological evaluation of novel selenonucleosides
Yao Chen1, Yingdan Peng, Jiancun Zhang
1School of Pharmacy, Shanghai Jiaotong University, Shanghai, PR China.
Nucleosides, Nucleotides & Nucleic Acids
|August 13, 2008
Abstract:
A series of novel selenonucleoside analogues with 1,4-oxaselenane as the carbohydrate fragment has been synthesized from their corresponding dimesylated seconucleosides treated with NaHSe solution and subsequent deprotection. The synthesized selenonucleoside analogues were evaluated as potential antitumor agents.

