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Characterization of nonspecific crossover in split-flow thin channel fractionation

P Stephen Williams1, Mauricio Hoyos, Pascal Kurowski

  • 1Department of Biomedical Engineering, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA. willias3@ccf.org

Analytical Chemistry
|August 14, 2008
PubMed
Summary

Split-flow thin channel (SPLITT) fractionation separates particles using a field-induced lateral migration. This study investigates nonspecific crossover (NSC) in SPLITT, exploring shear-induced diffusion (SID) as a potential cause.

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