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Updated: Jul 2, 2026

An All-in-one Sample Holder for Macromolecular X-ray Crystallography with Minimal Background Scattering
Published on: July 6, 2019
Simple adjustable liquid sample holder for x-ray absorption studies
Abstract:
A sample holder is described which permits the rapid optimization of liquid thickness for x-ray absorption fine structure studies. In particular it has been applied to the measurement of both Extended X-Ray Absorption Fine Structure (EXAFS) and near-edge structure in the vicinity of the K absorption edge of potassium ions (E(0) approximately equal to 3605 eV) in a variety of solutions. The instrument basically consists of a pair of blocks--one fixed and one movable, both with transparent x-ray windows of stretched polypropylene which sandwich a thin sealed liquid sample bag of polyethylene or polypropylene and which, through squeezing via a micrometer drive, are experimentally adjusted to yield the desired sample thickness.
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