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Related Experiment Video

Updated: Jul 2, 2026

Assembly and Operation of a Cooling Stage to Immobilize C. elegans on Their Culture Plates

Assembly and Operation of a Cooling Stage to Immobilize C. elegans on Their Culture Plates

Published on: May 5, 2023

Automatic 300-4 K temperature cycling apparatus.

C A Hamilton¹

¹National Bureau of Standards, Electromagnetics Division, Boulder, CO 80302, USA.

The Review of Scientific Instruments

|May 1, 1978

Summary

This summary is machine-generated.

This study introduces an automated apparatus for cycling small samples between 300 and 4 Kelvin. The device efficiently uses helium boil-off gas, minimizing liquid helium consumption for precise temperature control in experiments.

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Fabrication of Microscope Stage for Vertical Observation with Temperature Control Function

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Published on: July 31, 2019

Area of Science:

Cryogenics
Materials Science
Experimental Physics

Background:

Precise temperature control is crucial for various scientific investigations.
Traditional methods for sample temperature cycling can be complex and resource-intensive.

Purpose of the Study:

To develop an automated apparatus for rapid sample temperature cycling.
To minimize liquid helium consumption during low-temperature experiments.

Main Methods:

An apparatus automatically cycles samples between 300 K and 4 K.
Mechanical motion is achieved using a bellows system powered by helium boil-off gas.
The sample is moved through the neck of a liquid helium storage Dewar.

Main Results:

Liquid helium consumption is reduced to 0.03 liters per cycle for a 12-gram sample.
Achieved cycle times as short as 5 minutes.
Demonstrated efficient utilization of cooling from helium boil-off gas.

Conclusions:

The developed apparatus provides an efficient and automated method for low-temperature sample cycling.
This system significantly reduces cryogen consumption, making experiments more economical.
The rapid cycling capability enhances throughput for materials characterization and physical property measurements.