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Published on: October 12, 2012
A case of mucous membrane plasmacytosis successfully treated with cryotherapy
David James Najarian1, Babar K Rao, Amy S Pappert
1Department of Dermatology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, USA. djn6u@yahoo.com
Abstract:
Mucous membrane plasmacytosis is a rare, often idiopathic, inflammatory disorder that frequently presents as an erythematous, velvety, or lobulated plaque on a mucosal surface. While mucous membrane plasmacytosis often runs a benign course, plaques are known to erode, ulcerate, and bleed. Moreover, according to a recent review of mucous membrane plasmacytosis, treatments of this disorder are inconsistently successful. We report a case of erosive, hemorrhagic mucous-membrane plasmacytosis of the lips treated successfully with cryotherapy. To the best of our knowledge, this case represents the second case of mucous membrane plasmacytosis successfully treated with cryotherapy. The long term response of our patient's condition to cryotherapy with no functional side effects may warrant further study of this technique for severe erosive mucous membrane plasmacytosis.
Insights
Mucous membrane plasmacytosis, a rare inflammatory condition, can cause erosive, bleeding lesions. Cryotherapy offers a potentially effective treatment for severe lip cases, showing promising long-term results without side effects.
Area of Science:
- Dermatology
- Oral Medicine
Background:
- Mucous membrane plasmacytosis is a rare inflammatory condition.
- It often presents as plaques on mucosal surfaces, which can erode, ulcerate, and bleed.
- Current treatments for this disorder have inconsistent success rates.
Observation:
- A case of erosive, hemorrhagic mucous membrane plasmacytosis affecting the lips is presented.
- The condition caused significant discomfort and bleeding.
Findings:
- Cryotherapy was successfully employed to treat the lip lesions.
- The patient experienced long-term resolution of symptoms with no functional side effects.
Implications:
- Cryotherapy may be a viable treatment option for severe, erosive mucous membrane plasmacytosis.
- Further research into cryotherapy for this condition is warranted.
- This case highlights a potential therapeutic advance for a challenging disorder.

