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Supplemental programs for enhanced recovery of data from the DOTUR application
Sergio E Morales1, Theodore Cosart, Jesse V Johnson
1Microbial Ecology Program, Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA.
New downstream applications enhance the DOTUR program for analyzing large-scale clone libraries. These tools extract phylogenetic information and explore operational taxonomic unit (OTU) distribution from distance data.
Area of Science:
- Bioinformatics
- Computational Biology
- Phylogenetics
Background:
- Large-scale clone libraries generate complex distance matrices.
- Extracting phylogenetic information and OTU distribution from this data is challenging.
Purpose of the Study:
- To develop downstream applications for the DOTUR program.
- To enhance data extraction for phylogenetic analysis.
- To facilitate the exploration of OTU distribution.
Main Methods:
- Development of novel downstream applications.
- Integration with the existing DOTUR software.
- Application to distance matrices from large-scale clone libraries.
Main Results:
- Enhanced data extraction capabilities.
- Provided phylogenetic insights from distance data.
- Facilitated OTU distribution analysis.
Conclusions:
- The developed applications significantly improve the utility of DOTUR for phylogenetic studies.
- These tools simplify the retrieval of crucial ecological and evolutionary information from molecular data.
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