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Published on: November 27, 2016

Mesalazine pharmacokinetics and NAT2 phenotype.

Hendrik Lück1, Martina Kinzig, Alexander Jetter

  • 1Department of Pharmacology, University Hospital, University of Cologne, Cologne, Germany.

European Journal of Clinical Pharmacology
|August 16, 2008
PubMed
Summary

N-acetyltransferase type 2 (NAT2) does not significantly impact mesalazine metabolism in humans. This study found no correlation between NAT2 activity and mesalazine pharmacokinetics, suggesting NAT2 plays a minor role in its in vivo processing.

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