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Related Experiment Video

Updated: Jul 2, 2026

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
09:27

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability

Published on: April 22, 2016

Novel applications for microbial transglutaminase beyond food processing.

Yang Zhu1, Johannes Tramper

  • 1Food and Bioprocess Engineering Group, Wageningen University and Research Centre, 6700 EV Wageningen, The Netherlands. yang.zhu@wur.nl

Trends in Biotechnology
|August 19, 2008
PubMed
Summary

Microbial transglutaminase offers a cost-effective alternative to animal-derived enzymes for food applications. This review explores its broader potential beyond the food industry, highlighting recent advancements.

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Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
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Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
06:24

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Published on: December 15, 2017

Area of Science:

  • Biochemistry
  • Enzymology
  • Food Science

Background:

  • Transglutaminase (EC 2.3.2.13) was initially recognized for its meat-binding properties.
  • High costs of animal-derived transglutaminase spurred research into microbial sources.
  • Microbial transglutaminase production has been optimized since the early 1990s.

Purpose of the Study:

  • To review the expanding applications of microbial transglutaminase in the food sector.
  • To explore the largely untapped potential of transglutaminases in non-food applications.
  • To discuss recent research contributing to the realization of transglutaminase's full potential.

Main Methods:

  • Literature review of transglutaminase research and applications.
  • Analysis of microbial strain discovery and production optimization.
  • Assessment of current and potential transglutaminase uses across various industries.

Main Results:

  • Significant advancements in microbial transglutaminase production have led to widespread food industry adoption.
  • The potential of microbial transglutaminase in sectors beyond food remains largely underexplored.
  • Ongoing research is paving the way for novel applications of this versatile enzyme.

Conclusions:

  • Microbial transglutaminase presents a cost-effective and versatile enzymatic solution.
  • Further research and development are crucial to unlock the full spectrum of transglutaminase applications.
  • Expanding transglutaminase use beyond food holds significant promise for various scientific and industrial fields.