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Apelin/APJ signaling system: a potential link between adipose tissue and endothelial angiogenic processes

O Kunduzova1, N Alet, N Delesque-Touchard

  • 1Institut National de la Santé et de la Recherche Médicale, U858, Toulouse, Cedex 4, France. oxana.koundouzova@toulouse.inserm.fr

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
|August 19, 2008
PubMed
Summary

Apelin signaling is crucial for new blood vessel formation in adipose tissue. This study shows apelin, stimulated by hypoxia, promotes endothelial cell growth and vascular network development in fat grafts.

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