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Doppler ultrasonography: a tool for nephrologists--single centre experience

M Milovanceva-Popovska1, S Dzikova

  • 1Nephrology Clinic, Medical Faculty, Ss Cyril and Methodius University, Skopje, R. Macedonia. majamil.freemail.com.mk

Prilozi
|August 19, 2008
PubMed

Insights

Colour Doppler duplex ultrasonography (CDUS) noninvasively assesses kidney vascular changes. Resistive indexes (RIs) are valuable predictors for diabetic nephropathy and arteriolosclerosis, aiding diagnosis in transplant patients and suspected renal conditions.

Area of Science:

  • Nephrology
  • Radiology
  • Vascular Ultrasound

Background:

  • Colour Doppler duplex ultrasonography (CDUS) enables noninvasive assessment of vascular perfusion.
  • Ultrasound examinations using duplex Doppler apparatus have been standard since 1996.
  • Resistive indexes (RIs) are key metrics derived from kidney ultrasound.

Purpose of the Study:

  • To retrospectively evaluate the utility of CDUS in assessing kidney vascular conditions.
  • To determine if RI can predict outcomes in patients with Diabetic Nephropathy.
  • To assess the role of CDUS in diagnosing various renal pathologies including rejection, stenosis, and neoplasms.

Main Methods:

  • Retrospective analysis of 2581 CDUS examinations over three years (2005-2007).
  • Measurement of Resistive Indexes (RIs) in each kidney using scanner software.
  • Evaluation of transplant patients, diabetic nephropathy cases, and suspected renal artery stenosis, acute renal failure, and neoplasms.

Main Results:

  • Increased RI (> 0.68) was found in 108 patients with Diabetic Nephropathy.
  • Positive correlation between RI (> 0.64) and arteriolosclerosis severity in 331 patients.
  • CDUS identified pathological vascularization in suspected renal carcinoma (34 cases), testicular tumors (46 cases), prostate neoplasms (19 cases), and other tumors (32 cases).
  • CDUS also detected chronic rejection (98 cases), acute rejection (58 cases), and suspected renal artery stenosis/thrombosis (38 cases).

Conclusions:

  • CDUS, particularly RI measurement, is a valuable noninvasive tool for assessing kidney vascular health.
  • RI serves as a potential predictor for Diabetic Nephropathy and arteriolosclerosis.
  • CDUS provides crucial diagnostic information when combined with clinical and laboratory data for various renal conditions.

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