Related Experiment Video
Updated: Jul 2, 2026

The Murine Choline-Deficient, Ethionine-Supplemented (CDE) Diet Model of Chronic Liver Injury
Published on: October 21, 2017
[Characteristics of renal failure in chronic liver disease]
Abstract:
The aim of this study was to establish the characteristics of renal failure in patients with cirrhosis and compare their laboratory data on blood and urine with those of patients with chronic renal failure without liver disease; and then to correlate the data of patients with cirrhosis and renal failure with that of patients with cirrhosis without renal failure in relation to liver function There were three groups of patients: group A - patients with cirrhosis and renal failure; group K1-patients with cirrhosis without renal failure; and group K2-patients with chronic renal failure. The parameters of renal and liver function were also compared. The laboratory data on blood and urine in patients with cirrhosis and renal failure revealed characteristics of prerenal failure in a higher degree (functional renal failure). When liver failure was concerned there was no difference between patients with cirrhosis and renal failure and subjects with cirrhosis and no renal failure. The degree of renal failure was not always the same regarding the degree of liver failure although they can sometimes paralell.
More Related Videos
08:505/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
07:02Mouse Model of Acute to Chronic Kidney Disease Transition Induced by Renal Ischemia/Reperfusion Injury
Published on: February 10, 2026
Related Concept Videos
Effect of Hepatic Disease on Pharmacokinetics: Drug Dosing and Hepatic Blood Flow
Chronic Kidney Disease I: Introduction
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Chronic Kidney Disease II: Clinical Manifestations
Renal Failure: Dose Adjustments
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...