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Updated: Jul 2, 2026
06:22
Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats
Published on: April 14, 2023
Successful pregnancies post renal transplantation
Adnan Yaseen Alfi1, Mohamed Al-Amin Al-essawy, Mohamed Al-lakany
1Nephrology Department, King Abdul-Aziz Hospital and Oncology Center, Jeddah, Saudi Arabia. adnanalfi@yahoo.com.
Summary
Pregnancy after renal transplantation is associated with favorable maternal and fetal outcomes. Key risk factors for adverse events include elevated serum creatinine, hypertension, and a short interval post-transplant.
Area of Science:
- Nephrology
- Obstetrics
- Transplantation
Background:
- Renal transplantation significantly improves quality of life for patients with end-stage renal disease.
- Pregnancy in renal transplant recipients presents unique challenges and requires careful monitoring.
Purpose of the Study:
- To evaluate maternal and fetal outcomes in female renal transplant recipients.
- To identify risk factors associated with pregnancy post-renal transplantation.
Main Methods:
- Retrospective study of 20 pregnancies in 12 renal transplant recipients between 1989 and 2005.
- Analysis of donor type, maternal age, interval from transplantation to pregnancy, and clinical parameters.
Main Results:
- Mean gestational age at delivery was 36.3 weeks; mean fetal birth weight was 2349 gm.
- All neonates had Apgar scores of 9-10, with no intrauterine growth retardation or congenital anomalies.
- Urinary tract infections (25%) and preterm delivery were noted, associated with elevated creatinine and short post-transplant intervals.
Conclusions:
- Consecutive pregnancies in renal transplant recipients can achieve long-term maternal and fetal survival and function.
- Elevated serum creatinine, hypertension, and short time interval from transplantation to pregnancy are major risk factors.
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