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Updated: Jul 2, 2026

05:58
Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
Published on: September 11, 2013
[Asteroid hyalosis within an epiretinal membrane]
D Süsskind1, F Gelisken, J Rohrbach
1Department für Augenheilkunde, Eberhard-Karls-Universität Tübingen. daniela.suesskind@med.unituebingen.de
Summary
Asteroid hyalosis, a vitreous degenerative disorder, can complicate proliferative diabetic retinopathy surgery. This case highlights an unusual foreign body reaction to asteroid bodies within an epiretinal membrane during vitrectomy.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Vitreous Disorders
Background:
- Asteroid hyalosis is a common vitreous degenerative disorder.
- Its etiology and pathogenesis remain unclear.
- Associated with systemic conditions like diabetes mellitus and hypertension.
Observation:
- An 80-year-old male with diabetic retinopathy presented with decreased visual acuity.
- Thick asteroid hyalosis precluded fundus examination.
- Vitreoretinal traction was identified sonographically, necessitating vitrectomy.
Findings:
- Microscopic examination revealed amorphous bodies, positive with PAS staining.
- These bodies were embedded in a fibrovascular stroma.
- A foreign body reaction with giant cells was observed around the asteroid bodies.
Implications:
- Surgery for proliferative diabetic retinopathy was required.
- Incorporation of asteroid bodies into an epiretinal membrane is unusual.
- This can induce a foreign body reaction, complicating surgical outcomes.

