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Updated: Jul 2, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

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Published on: June 13, 2018

Folliculitis decalvans.

Nina Otberg¹, Hoon Kang, Abdullateef A Alzolibani

¹Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada. ninaotberg@gmx.com

Dermatologic Therapy

|August 22, 2008

Summary

This summary is machine-generated.

Folliculitis decalvans is a rare inflammatory scalp condition affecting middle-aged adults, often linked to Staphylococcus aureus and immune response. Early diagnosis and management are key to treating this disfiguring alopecia.

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Area of Science:

Dermatology
Pathology

Background:

Folliculitis decalvans is a rare, primary neutrophilic cicatricial alopecia.
It predominantly affects middle-aged adults, causing disfigurement.

Purpose of the Study:

To provide a practical approach to the diagnosis and management of folliculitis decalvans.
To review potential pathogenetic factors and treatment strategies.

Main Methods:

Clinical presentation analysis.
Histopathological examination of lesions.
Review of existing literature on pathogenesis and treatment.

Main Results:

Folliculitis decalvans presents with follicular pustules, erythema, and crusts, primarily on the vertex and occipital scalp.
Histology shows a neutrophilic infiltrate, progressing to include lymphocytes and plasma cells.
Staphylococcus aureus and a compromised host immune response are implicated in its development.

Conclusions:

Effective management requires addressing Staphylococcus aureus and employing anti-inflammatory agents.
Understanding the pathogenesis aids in developing targeted treatment options.