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Superior Auto-Identification of Trypanosome Parasites by Using a Hybrid Deep-Learning Model
Published on: October 27, 2023
What happens when Trypanosoma brucei leaves Africa
Robert E Jensen1, Larry Simpson, Paul T Englund
1Department of Cell Biology, Johns Hopkins Medical School, Baltimore, MD 21205, USA.
Abstract:
Julius Lukes and co-workers evaluated the evolutionary origin of Trypanosoma equiperdum and Trypanosoma evansi, parasites that cause horse and camel diseases. Although similar to T. brucei, the sleeping-sickness parasite, these trypanosomes do not cycle through the tsetse fly and have been able to spread beyond Africa. Transmission occurs sexually, or via blood-sucking flies or vampire bats. They concluded that these parasites, which resemble yeast petite mutants, are T. brucei sub-species, which have evolved recently through changes in mitochondrial DNA.
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