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Jejunal ischaemia-- rare aetiologies and a surgical dilemma

F Geranmayeh1, S Usman, R Bhutiani

  • 1Department of surgery, Central Middlesex Hospital, North West London Hospitals NHS trust, London NW10 7NS, UK.

Acta Gastro-Enterologica Belgica
|August 30, 2008
PubMed

Insights

Superior Mesenteric Artery thrombosis causes acute mesenteric ischemia. Delayed diagnosis, often due to undiagnosed Antiphospholipid Syndrome and Factor V Leiden, prolongs patient morbidity.

Area of Science:

  • Vascular Surgery
  • Gastroenterology
  • Hematology

Background:

  • Superior Mesenteric Artery (SMA) thrombosis is a critical condition leading to acute mesenteric ischemia.
  • Diagnosis is often delayed due to subtle initial symptoms, progressing to infarction and perforation.

Observation:

  • A unique case of jejunal ischemia is presented.
  • The patient had undiagnosed Antiphospholipid Syndrome and Factor V Leiden heterozygosity.
  • Diagnosis was significantly delayed, leading to prolonged patient morbidity.

Findings:

  • Undiagnosed Antiphospholipid Syndrome and Factor V Leiden heterozygosity can predispose individuals to SMA thrombosis.
  • Delayed diagnosis of mesenteric ischemia exacerbates patient outcomes.

Implications:

  • Early screening for thrombophilia in patients with unexplained mesenteric ischemia is crucial.
  • Prompt diagnosis and management of SMA thrombosis can prevent severe complications and reduce morbidity.

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