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Updated: Jul 2, 2026

Gas Chromatography-Mass Spectrometry Paired with Total Vaporization Solid-Phase Microextraction as a Forensic Tool
Published on: May 25, 2021
Importance of extracting solvent vapor pressure in headspace liquid-phase microextraction
Xue Yan1, Cui Yang, Chunyan Ren
1Department of Chemistry, College of Science, Yanbian University, Park Road 977, Yanji City 133002, Jilin Province, China.
Abstract:
Of the many parameters that affect the enrichment factors in headspace liquid-phase microextraction, in this study, we systematically investigated the influence of the vapor pressure of the extracting solvent. Seven extracting solvents with different vapor pressures were selected and tested. It was found that the vapor pressure of the extracting solvent dramatically affects the enrichment factor and the factor was increasing by decreasing the extracting solvent vapor pressure under given experimental conditions. The result was validated for volatile organic compounds such as polynuclear aromatic hydrocarbons, organochlorine pesticides and polychlorinated biphenyls.
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