Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Secondary Lymphoid Organs

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...

Lymphoid Cells and Tissues

Lymphoid Cells and Tissues

Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...

Appendicitis-I: Introduction

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

Primary Lymphoid Organs

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...

Cells of the Adaptive Immune Response

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

QSPR analysis of the drugs used to treat major depressive disorder using degree and neighborhood degree based indices.

Frontiers in chemistry·2026

Same author

Artificial intelligence in pathology: A descriptive survey of awareness, acceptance, and implementation challenges among pathologists in Telangana and Andhra Pradesh.

Indian journal of pathology & microbiology·2026

Same author

Association between regional anaesthesia strategies, postoperative pain and same-day discharge following knee arthroplasty: a single-centre service evaluation.

BMC anesthesiology·2026

Same author

QSPR analysis of the drugs used to treat renal failure and its complications using degree and modified reverse degree indices.

Scientific reports·2026

Same author

QSPR analysis of anti-HIV drugs using neighborhood degree sum-based topological indices.

The European physical journal. E, Soft matter·2025

Same author

Enhancing sparse data recommendations with self-inspected adaptive SMOTE and hybrid neural networks.

Scientific reports·2025

Search research articles

Related Experiment Video

Updated: Jul 2, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

Primary marginal zone B-cell lymphoma of appendix.

S Radha¹, Tameem Afroz, G Satyanarayana

¹Department of Pathology and General Surgery, Kamineni Hospitals, L.B. Nagar, Hyderabad, India. sradha_21@hotmail.com

Indian Journal of Pathology & Microbiology

|August 30, 2008

Summary

Primary appendix lymphomas are rare gastrointestinal tumors. Histological examination of all appendicectomy specimens is crucial for diagnosing these rare marginal zone B-cell lymphomas.

More Related Videos

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Related Experiment Videos

Last Updated: Jul 2, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Area of Science:

Gastrointestinal oncology
Surgical pathology

Background:

Primary lymphomas of the appendix are exceptionally rare neoplasms.
The incidence of primary appendix lymphoma is approximately 0.015% of all gastrointestinal lymphomas.
First documented in 1898, these tumors remain a diagnostic challenge.

Observation:

This report details a case of primary marginal zone B-cell lymphoma of the appendix.
The lymphoma presented clinically as an appendicular mass.
Some cases are discovered incidentally during routine pathological examination.

Findings:

The case highlights a primary marginal zone B-cell lymphoma of the appendix.
The clinical presentation mimicked a common appendicular mass.

Implications:

Mandatory histological examination of all appendicectomy specimens is essential for accurate diagnosis.
Early detection through thorough pathological review can improve patient outcomes.
This emphasizes the importance of considering rare differentials in appendiceal pathology.